反应详情

Cis-4-cyclohexene-1,2-dicarboxylic anhydride (7.6 g., 0.05 mole) was dissolved in 150 ml. 1,2-dimethoxyethane and 4.7 g. aniline (0.05 mole) was added. The reaction mixture was heated to reflux for one hour and allowed to stand overnight. The solvent was evaporated. The product then obtained was purified by pouring into 200 ml. of 10% hydrochloric acid solution. This was extracted with diethyl ether, dried over anhydrous magnesium sulfate, filtered and the solvent stripped off. There was obtained 7.3 g. of the title compound. The structure was confirmed by infrared analysis and n.m.r.

1. temperatureThe reaction mixture was heated
2. temperatureto reflux for one hour
3. customThe solvent was evaporated
4. customThe product then obtained
5. customwas purified
6. additionby pouring into 200 ml
7. extractionThis was extracted with diethyl ether
8. dry with materialdried over anhydrous magnesium sulfate
9. filtrationfiltered
10. customThere was obtained 7.3 g