HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 20286704, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | ethyl 5-chloro-3-phenyl-1H-indole-2-carboxylate | HCID 737953 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 20286704 | HCID 20286704 | — |
Reaction Steps
Add 11 ml (33 g.) of bromine to a mixture of ethyl 5-chloro-3-phenylindole-2-carboxylate (30 g.) in 100 ml of acetic acid at 10°-20° . Stir overnight and then add a solution of sodium bisulfite. Filter and wash the precipitate with water. Stir the solid with methanol and filter to yield the title compound. Recrystallization from methanol yields the analytical sample; m.p. 205°-206° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996159 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-0125e6f1c130417ea063a6343805d11d |
| Source note | uspto-grants-1976_12 |