HCID 12560493, compound → HCID 21492747, compound

HRID 1973094Notes

Reaction equation

HRID 1973094 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3[CH:12]=[C:13]([O:16][CH3:17])[CH:14]=[CH:15][C:9]=3[CH2:8][CH:7](Cl)[C:6]=2[CH:19]=1.[CH2:20]([N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1)[C:21]#[CH:22]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[S:11][C:10]3[CH:12]=[C:13]([O:16][CH3:17])[CH:14]=[CH:15][C:9]=3[CH2:8][CH:7]([N:26]3[CH2:27][CH2:28][N:23]([CH2:20][C:21]#[CH:22])[CH2:24][CH2:25]3)[C:6]=2[CH:19]=1

Participants

3

Reactant 2

HCID 12560493HCID 12560493, compoundHCID 146273691-(2-Propynyl)piperazine

Product 1

HCID 21492747HCID 21492747, compound

Procedure

In a manner analogous to that described in Example 1, from 8,10-dichloro-10,11-dihydro-3-methoxy-dibenzo[b,f]thiepin and N-(2-propynyl)-piperazine there is obtained 1-[8-chloro-10,11-dihydro-3-methoxy-dibenzo[b,f]thiepin-10-yl]-4-(2-propynyl)-piperazine, the dimethanesulfonate of which melts at 177°-180° C.

Sources & evidence

ORD record
ord-ed9171b3db194ac8b29bff0bbd326d76
Source dataset
uspto-grants-1976_12
Patent number
US03996229

Reaction notes

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