HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 10,11-Dihydro-3-methoxy-8-methylthio-dibenzo[b,f]thiepin-10-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | 3-methoxy-8-methylthio-dibenzo[b,f]thiepin-10(11H)-one | HCID 12822195 | — |
| Solvent | Water | HCID 962 | — |
| Product | 10,11-Dihydro-3-methoxy-8-methylthio-dibenzo[b,f]thiepin-10-ol | HCID 12822198 | — |
Reaction Steps
17.8 G. of 3-methoxy-8-methylthio-dibenzo[b,f]thiepin-10(11H)-one are suspended in 150 ml. of ethanol and treated with 3.8 g. of sodium borohydride. The mixture is stirred for 90 minutes. Then, it is treated with water and extracted with ether. The organic phase is washed with water, dried over magnesium sulfate, evaporated, and there is obtained 10,11-dihydro-3-methoxy-8-methylthio-dibenzo[b,f]thiepin-10-ol having a melting point of 122°-124° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996229 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-c1dec78aba7e49dda5666e2b32b88a19 |
| Source note | uspto-grants-1976_12 |