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HRID1973112

反应详情

EQUATION

反应方程式

HRID 1973112 的结构方程式

REACTANTS

反应物

2
结构：CNN
HCID6061

Methylhydrazine

CH6N2

结构：CCOC(=O)c1c(C)nc(Cl)c([N+](=O)[O-])c1Cl
HCID12387594

Ethyl 4,6-dichloro-2-methyl-5-nitropyridine-3-carboxylate

C9H8Cl2N2O4

PRODUCTS

生成物

1
结构：CCOC(=O)c1c(C)nc(N(C)N)c([N+](=O)[O-])c1Cl
HCID12387613

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

27.9 g. of 4,6-dichloro-2-methyl-5-nitropyridine-3-carboxylic acid, ethyl ester (0.1 Mol.) are dissolved in about 100 ml. of methanol. At 50°, 9.2 g. of methylhydrazine are dropped in and the mixture is stirred for 30 minutes. On cooling, 4-chloro-6-(1-methyl)hydrazino-2-methyl-5-nitropyridine-3-carboxylic acid, ethyl ester precipitates, yield: 18 g. (62.2%), m.p. 159°-161° (methanol).

WORKUP

后处理

  1. customAt 50°
  2. temperatureOn cooling
  3. custom4-chloro-6-(1-methyl)hydrazino-2-methyl-5-nitropyridine-3-carboxylic acid, ethyl ester precipitates