HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 54095776, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Reactant | 1-Iodo-3-methyloct-1-en-3-ol | HCID 54522683 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 54095776 | HCID 54095776 | — |
Reaction Steps
A solution of 2.625 g. of dl-1-iodo-3-methyl-1-octen-3-ol, 3.2 g. of imidazole and 3.6 g. of t-butyldimethylsilyl chloride in 10 ml. of dimethylformamide is stirred at 60° C. for 35 hours under nitrogen. After vacuum evaporation of the solvent, the residue is extracted with hexane and chromatogaphed on neutral alumina (Activity 3). Elution with hexane gives the title product as an oil, 2.15 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996255 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-605d4a5ac4294a878900a85fd227a69d |
| Source note | uspto-grants-1976_12 |