HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 14284973, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 6-Bromo-1-hexanol | HCID 77970 | — |
| Reactant | HCID 86734239 | HCID 86734239 | — |
| Product | HCID 14284973 | HCID 14284973 | — |
Reaction Steps
The use of a protected derivative of 6-bromohexanol can be avoided. Thus, an excess of lithium (E)-5-decen-1-yne in liquid ammonia is used and allowed to react directly with 6-bromohexanol to give (E)-11-hexadecen-7-yne-1-ol, bp 134°-136°/1 mm, nD21 1,4755. Acetylation converts the alcohol to the above acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996270 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-d70a888edb6d485487bbc5bfcaf9cf88 |
| Source note | uspto-grants-1976_12 |