Dimepranol → HCID 20337003, compound

HRID 1973220Notes

Reaction equation

HRID 1973220 reaction equation
[CH3:1][N:2]([CH3:7])[CH2:3][CH:4]([OH:6])[CH3:5].[CH3:8][O:9][C:10]1[CH:17]=[CH:16][C:13]([CH2:14][Cl:15])=[CH:12][C:11]=1[N+:18]([O-:20])=[O:19]>O>[Cl-:15].[N+:18]([C:11]1[CH:12]=[C:13]([CH:16]=[CH:17][C:10]=1[O:9][CH3:8])[CH2:14][N+:2]([CH2:3][CH:4]([OH:6])[CH3:5])([CH3:7])[CH3:1])([O-:20])=[O:19]

Participants

4

Reactant 2

HCID 37511DimepranolHCID 807854-(Chloromethyl)-2-nitroanisole

Product 1

HCID 20337003HCID 20337003, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Proceeding in a manner similar to that described above in D -la, 16 parts of 1-dimethylamino-2-propanol and 32 parts of 4-methoxy-3-nitrobenzyl chloride were interacted in 14 parts of water to obtain N-(3-nitro-4-methoxybenzyl)-N-(2-hydroxy-propyl)-N,N-dimethylammonium chloride. The product was not isolated but was used directly in solution for reduction of the nitro group.

Sources & evidence

ORD record
ord-2941254d62b04d56bac3f8a594342061
Source dataset
uspto-grants-1976_12
Patent number
US03996282

Reaction notes

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