HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → Xanthydrol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Xanthone | HCID 7020 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Phenoxybenzoic acid | HCID 75237 | — |
| Catalyst | Copper | HCID 23978 | — |
| Catalyst | Sodium amalgam | HCID 9837419 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Xanthydrol | HCID 72861 | — |
Reaction Steps
The xanthydrols are either known to the art or are prepared by the following procedure. A 2-halobenzoic acid is reacted with a phenol preferably in the presence of a base such as potassium carbonate and in the presence of cuprous iodide and copper bronze. The resulting 2-phenoxybenzoic acid is cyclized by treating with acid for example polyphosphoric acid. The resulting xanthone is reduced, for example using sodium amalgam in ethanol, to give the xanthydrol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996364 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-ee6100cc453c4a1c92d57be713d8b2f0 |
| Source note | uspto-grants-1976_12 |