HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 21493433, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Naphthalimide | HCID 66491 | — |
| Reactant | 1,3-Dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one | HCID 88638 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 21493433 | HCID 21493433 | — |
Reaction Steps
An equimolar mixture of 1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one, aqueous formaldehyde and 1,8-naphthalimide is suspended in a small amount of dimethylformamide and the mixture is heated until dissolution is complete. The solution is allowed to stand at room temperature and the resulting precipitate is filtered off and dried to yield 2-[1-[4-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-1-piperidinyl]methyl]-1H-benz[de]isoquinoline-1,3(2H)-dione.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996362 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-5f5d8846954641d0b12c4ab3e71b65fd |
| Source note | uspto-grants-1976_12 |