HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Chloro-N,N-dimethyl-4-(2-nitroprop-1-en-1-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Nitroethane | HCID 6587 | — |
| Reactant | Benzaldehyde, 2-chloro-4-(dimethylamino)- | HCID 74021 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Chloro-N,N-dimethyl-4-(2-nitroprop-1-en-1-yl)aniline | HCID 53649832 | — |
Reaction Steps
A solution of 36.8 g of 2-chloro-4-dimethylaminobenzaldehyde, 18 ml of nitroethane and 15 g of ammonium acetate in 150 ml of absolute ethanol is refluxed for 2 hours. The mixture is then poured into 1.5 l of water, whereupon the compound separates as a viscous red oil, which crystallizes on scratching. Recrystallization from ethanol yields 18.0 g of the compound, melting at 93°-94°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996381 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-21e7c60418b5445a92f6422166d99707 |
| Source note | uspto-grants-1976_12 |