HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Chloro-N,N-dimethyl-4-(2-nitrobut-1-en-1-yl)aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Nitropropane | HCID 7903 | — |
| Reactant | Benzaldehyde, 2-chloro-4-(dimethylamino)- | HCID 74021 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Solvent | 1-Propanol | HCID 1031 | — |
| Product | 3-Chloro-N,N-dimethyl-4-(2-nitrobut-1-en-1-yl)aniline | HCID 53769841 | — |
Reaction Steps
A solution of 36.8 g of 2-chloro-4-dimethylaminobenzaldehyde, 25 ml of 1-nitropropane and 20 g of ammonium acetate in 150 ml of 1-propanol is refluxed for 15 hours. The mixture is then poured into 1.5 l of water whereupon the compound separates as a viscous red oil. Recrystallization twice from aqueous acetic acid yields 5.0 g of the compound, melting at 90°-91°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996381 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-5cd59fdbbb5d499e831ee925c4e442b0 |
| Source note | uspto-grants-1976_12 |