HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Diethylethylenediamine → 2H-Isoindole-1-carboxylic acid, 5-chloro-2-(2-(diethylamino)ethyl)-3-phenyl-, ethyl ester, monohydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Diethylethylenediamine | HCID 60993 | — |
| Reactant | o-Benzoyl-p-chloro-phenylglyoxylic acid ethyl ester | HCID 54162441 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 2H-Isoindole-1-carboxylic acid, 5-chloro-2-(2-(diethylamino)ethyl)-3-phenyl-, ethyl ester, monohydrochloride | HCID 3045893 | — |
Reaction Steps
In a manner analogous to that described in Example 19, from 0.95 g. of o-benzoyl-p-chloro-phenylglyoxylic acid ethyl ester, 1.05 g. of 2-diethylaminoethylamine and 0.83 g. of formic acid, there is obtained 5-chloro-2-[2-(diethylamino)ethyl]-3-phenylisoindole-1-carboxylic acid ethyl ester hydrochloride; melting point 248°-250° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03996374 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-0e1acb25c5f84791ae1aabee19f348c3 |
| Source note | uspto-grants-1976_12 |