Hydrochloric Acid → HCID 54153306, compound

Participants

Reaction Conditions

Reaction Steps

4-Amino-2-benzyl-5-carbethoxy-1-methyl-imidazole (30g.) was suspended in water (12 ml.) containing conc. HCl -- (12 ml) and a solution of sodium nitrite (0.96 g.) in water (5 ml.) slowly added with stirring at 0° C. After addition was complete this solution was added to a stirred solution of Na2CO3 (118 ml, 30%) and aqueous dimethylamine (2.5 ml, 25%) added dropwise at 0° C added with stirring. After half an hour the brown precipitate was filtered off, washed with water and dried. Crystallisation from ethylacetate/petrol yielded 2-benzyl-5-carbethoxy-(3,3-dimethyltriazeno)-1-methylimidazole (1g, 27%) m.p. 107°-108° C (dec).

Provenance & Evidence