HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → N-{[3-(Bromomethyl)thiophen-2-yl]methyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | N-[(3-Methylthiophen-2-yl)methyl]acetamide | HCID 21452353 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | N-{[3-(Bromomethyl)thiophen-2-yl]methyl}acetamide | HCID 20311374 | — |
Reaction Steps
N-Acetyl-2-aminomethyl-3-methylthiophene is dissolved in carbon tetrachloride and treated with an equimolar amount of N-bromosuccinimide and a catalytic amount of dibenzoyl peroxide. The mixture is heated to reflux for 3 hours while irradiating with a 250 watt light. The mixture is cooled and the precipitated succinimide removed by filtration. The filtrate is washed with saturated sodium bisulphite solution, dried over magnesium sulfate and evaporated to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03997527 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-e1a77dd5dacc4e2cbfe90ad4c57ba23f |
| Source note | uspto-grants-1976_12 |