HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1973434Generated: November 1, 2026
Benzoyl chloride → N-isopropyl-N-(3,4-methylenedioxyphenyl)-N'-benzoyl thiourea
https://huagongshe.com/reaction/1973434
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Benzoyl isothiocyanate | HCID 68284 | — |
| Reactant | Isothiocyanatosodium | HCID 10953423 | — |
| Reactant | 1-Isopropylamine 3,4-methylenedioxybenzene | HCID 86734257 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | N-isopropyl-N-(3,4-methylenedioxyphenyl)-N'-benzoyl thiourea | HCID 12789467 | — |
Reaction Steps
To a solution of 16.3 grams benzoyl isothiocyanate, prepared by refluxing 13.6 grams of dried sodium isothiocyanate with 17 grams of benzoyl chloride in 30 ml. of benzene, is slowly added, at room temperature, 28 grams of N-isopropyl-N-(3,4-methylenedioxyphenyl)-amine (prepared as in Example A) in 150 ml. benzene. The reaction mixture is stirred for 30 minutes at 20°C. and a solid forms which is recrystallized from benzene to yield N-isopropyl-N-(3,4-methylenedioxyphenyl)-N'-benzoyl thiourea melting at 152°-154°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US03997564 |
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| Source dataset | uspto-grants-1976_12 |
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| ORD ID | ord-a07019530c7c47cfb39c5beffc951ad7 |
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| Source note | uspto-grants-1976_12 |
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