HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 21491579, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Oxalic Acid | HCID 971 | — |
| Reactant | N-Methyl-1,3-propanediamine | HCID 80511 | — |
| Reactant | Cyclopentanone, 2-(2-oxo-2-phenylethyl)- | HCID 10655725 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 21491579 | HCID 21491579 | — |
Reaction Steps
8.82 g (0.1 mole) of methylaminopropylamine are added to a solution of 20.35 g (0.1 mole) of 2-phenacylcyclopentanone in glacial acetic acid under nitrogen. After refluxing for 12 hours, water is added and the aqueous solution is washed with ether. The aqueous phase is basified with sodium carbonate and extracted with ether to give a reddish oil. The oil is dissolved in ether and is added to an ether solution of oxalic acid to give 1-(3-methylaminopropyl)-2-phenyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole oxalate, m.p. 184°-185° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03997557 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-4e4e697c1eef45d78e4efdd60526691f |
| Source note | uspto-grants-1976_12 |