Acetic Anhydride → HCID 21491951, compound

HRID 1973550Notes

Reaction equation

HRID 1973550 reaction equation
[C:1]([C:3]1[C:8]([CH:9]([CH3:11])[CH3:10])=[CH:7][C:6]([S:12]([NH2:15])(=[O:14])=[O:13])=[C:5]([CH:16]([CH3:18])[CH3:17])[CH:4]=1)#[N:2].[C:19](OC(=O)C)(=[O:21])[CH3:20]>>[C:19]([NH:15][S:12]([C:6]1[CH:7]=[C:8]([CH:9]([CH3:11])[CH3:10])[C:3]([C:1]#[N:2])=[CH:4][C:5]=1[CH:16]([CH3:18])[CH3:17])(=[O:14])=[O:13])(=[O:21])[CH3:20]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 21491925HCID 21491925, compound

Product 1

HCID 21491951HCID 21491951, compound

Procedure

A mechanically stirred mixture of 8 parts of 4-cyano-2,5-diisopropylbenzenesulfonamide and 50 parts of acetic anhydride was heated near reflux for 6 hours. The reaction was concentrated in vacuo to give a solid which was recrystallized from ethanol-water, and then exhibited a m.p. of 170°-173°.

Workup

  1. temperaturewas heated
  2. temperaturenear reflux for 6 hours
  3. concentrationThe reaction was concentrated in vacuo
  4. customto give a solid which
  5. customwas recrystallized from ethanol-water

Sources & evidence

ORD record
ord-f491cfdbd6104c91b8cbde49c16ac95e
Source dataset
uspto-grants-1976_12
Patent number
US03997603

Reaction notes

Loading…