Acetic acid, 2-(triphenylphosphoranylidene)-, ethyl ester → HCID 53694640, compound

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Reaction Steps

A mixture of 27.3 g of 1-[3-(2-methyl-2-dioxolanyl)propyl]-3-indolecarboxaldehyde (0.1 mole) and 40 g. (0.11 mole) of carbethoxymethylene triphenylphosphorane in 400 ml. of toluene is heated at reflux overnight. The resulting cold solution is filtered through a Silica gel column to remove the inorganic material to give 1-[3-(2-methyl-2-dioxolanyl)propyl]-3-indoleacrylic acid ethyl ester, m.p. 61°-62° C.

Provenance & Evidence