反应详情

A solution containing 20 parts of (5-chloropentanoylmethylene)triphenylphosphorane in 200 parts of benzene is heated at the reflux temperature for about 16 hours. Cooling of this solution results in crystallization of a product which is isolated by filtration to afford [(tetrahydro-2H-pyran-2-ylidene)]methyltriphenylphosphonium chloride. This product is characterized by 60-MHz nuclear magnetic resonance peaks in CDCl3 (deuterated chloroform) at about 107 cps (multiplet), 170 cps (multiplet), 228 cps (multiplet) and 329 cps (doublet, J≃18 cps) in addition to the aromatic protons. This compound melts at about 215-221° C. and is represented by the following structure: ##STR8##

1. temperatureis heated at the reflux temperature for about 16 hours
2. temperatureCooling of this solution
3. customresults in crystallization of a product which
4. customis isolated by filtration