Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Malonic Acid | HCID 867 | — |
| Reactant | Benzaldehyde, 4-hexyl- | HCID 170813 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | p-n-Hexylcinnamic acid | HCID 53878923 | — |
Reaction Steps
9.4 G. of p-n-hexylbenzaldehyde in 5 ml. of absolute pyridine are treated with 5.15 g. of malonic acid and 5 drops of piperidine. The mixture is then heated at 100° C. for 11 hours, subsequently poured on to cold aqueous hydrochloric acid and extracted with ether. The p-n-hexylcinnamic acid obtained after recrystallization of the crude product from hexane/ether has a melting point of 107°-109° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03997536 |
|---|
| Source dataset | uspto-grants-1976_12 |
|---|
| ORD ID | ord-808f5a798aad47faa36586fda8b11198 |
|---|
| Source note | uspto-grants-1976_12 |
|---|
