反应详情

The 2,5-diketo-D-gluconic acid produced by culturing Strain A in the medium or by the direct contact of the substrate with any processed product of Strain A and accumulated in a broth of crude state, may be, without being isolated, utilized by Strain B or reduced by any processed product of Strain B to be converted into 2-keto-L-gulonic acid. Alternately, the 2-keto-D-gluconic acid which would be by-produced, if the pure, unmixed culture of Strain B should be conducted, can be utilized by Strain A or oxidized by any processed product of Strain A to produce 2,5-diketo-D-gluconic acid which may subsequently be converted again into 2-keto-L-gulonic acid.

1. customwithout being isolated