Hydrochloric Acid → HCID 21490209, compound

Participants

Reaction Steps

One part by weight of 1,4-dimorpholino-7-phenylpyrido(3,4-d)pyridazine is dissolved in 50 parts by volume of ethanol under warming. Ten parts by volume of a 10% hydrogen chloride ethanolic solution is added to the solution and the resulting mixture is cooled to precipitate 1,4-dimorpholino-7-phenylpyrido(3,4-d)pyridazine hydrochloride. The product (one part by weight) is collected by filtration and recrystallized from 50 parts by volume of ethanol to obtain highly purities 1,4-dimorpholino-7-phenylpyrido(3,4-d)-pyridazine hydrochloride melting at 176° to 181° C as orange needles. Elementary analysis for C21H24O2N5Cl

Provenance & Evidence