HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1973667Generated: November 1, 2026
3-Aminocyclohex-2-en-1-one → 3-Methyl-7,8-dihydroquinolin-5(6H)-one
https://huagongshe.com/reaction/1973667
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Aminocyclohex-2-en-1-one | HCID 78892 | — |
| Reactant | 3-Ethoxy-2-methyl-2-propenal | HCID 559198 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-Methyl-7,8-dihydroquinolin-5(6H)-one | HCID 595192 | — |
Reaction Steps
A mixture of 3-aminocyclohex-2-enone (24.1g, 0.22m) and 3-ethoxy-2-methylacrolein (27.7g, 0.24m) in glacial acetic acid (55 ml.) was heated at reflux for 24 hours, cooled to 0° C and filtered. The solid (5g.) was recrystallised from ethanol as colourless needles m.p. 253° and identified di(2-methylprop-2-enalyl)amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US03998831 |
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| Source dataset | uspto-grants-1976_12 |
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| ORD ID | ord-749abd9c823b4f22a93a170c00fc7d70 |
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| Source note | uspto-grants-1976_12 |
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