HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3-Methyl-7,8-dihydroquinolin-5(6H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 3-Ethoxy-2-methyl-2-propenal | HCID 559198 | — |
| Reactant | HCID 3781742 | HCID 3781742 | — |
| Product | 3-Methyl-7,8-dihydroquinolin-5(6H)-one | HCID 595192 | 4% |
Reaction Steps
A mixture of 3-aminocyclohex-2-enone (11.1 g. 0.1m) and 3-amino-2-methylacrolein (8.5 g. 0.1 m) in toluene (15 ml.) was heated at reflux below a Dean and Stark water separator for 48 hours. The solvent was removed and the residual oil distilled at 0.2 mm Hg to give the title compound as a colourless crystalline solid (0.5 g, 4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03998831 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-ad1a43e94222450190ac65f1feb3ee72 |
| Source note | uspto-grants-1976_12 |