HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzoyl chloride → HCID 18424318, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzoyl chloride | HCID 8502 | — |
| Reactant | Ethyl 1,4-dimethyl-1H-pyrrole-2-acetate | HCID 118467 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 18424318 | HCID 18424318 | 85% |
Reaction Steps
A solution of 7.24 g (0.04 mole) of ethyl 1,4-dimethylpyrrole-2-acetate and 11.1 g (0.06 mole) of p-nitrobenzoyl chloride in 30 ml of ether under argon is stirred at room temperature in the dark for two days. The precipitate is collected by filtration. Recrystallization from isopropanol gives 11.2 g (85% yield) of ethyl 1,4-dimethyl-5-(p-nitrobenzoyl)pyrrole-2-acetate as yellow crystals, m.p. 148°-149° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03998844 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-0c0a586bb0644e12a12b46c86a568bc3 |
| Source note | uspto-grants-1976_12 |