HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride, 3,4-dichloro- → Ethyl 5-(3,4-dichlorobenzoyl)-1,4-dimethylpyrrole-2-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride, 3,4-dichloro- | HCID 76403 | — |
| Reactant | Ethyl 1,4-dimethyl-1H-pyrrole-2-acetate | HCID 118467 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | Ethyl 5-(3,4-dichlorobenzoyl)-1,4-dimethylpyrrole-2-acetate | HCID 21490352 | 80% |
Reaction Steps
A solution of 3.6 g of ethyl 1,4-dimethylpyrrole-2-acetate and 8.3 g of 3,4-dichlorobenzoyl chloride in 20 ml of xylene is refluxed for 40 min and then chilled. The separated solid is collected by filtration and dried to give 5.6 g (80%) of ethyl 5-(3,4-dichlorobenzoyl)-1,4-dimethylpyrrole-2-acetate as white crystals, m.p. 92°-93.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03998844 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-0f1583e33f3c42589f31915499461a11 |
| Source note | uspto-grants-1976_12 |