HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 3alpha-Acetoxy-5alpha-pregnane-11,20-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Alphaxalone | HCID 104845 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3alpha-Acetoxy-5alpha-pregnane-11,20-dione | HCID 11872797 | — |
Reaction Steps
A solution of 3α-hydroxy-5α-pregnane-11,20-dione (1 g) in pyridine (ca 5 ml) was treated with acetic anhydride (2.5 ml) and allowed to stand overnight. The reaction mixture was poured into water and the solid collected by filtration and dried to give the title compound m.p. 150°-151°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03998829 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-25e966eb05ea4922a5fa0331b4c1c324 |
| Source note | uspto-grants-1976_12 |