Sulfuric Acid → HCID 20393454, compound

Participants

Reaction Conditions

Reaction Steps

To 0.5 moles of fluorobenzene and 0.2 moles of sulfuric acid at 80° C is added portionwise 0.2 , moles of gamma-carboxy-gamma-valerolactone (I). The mixture is kept at 80° C for an additional hour. The mixture is cooled to 10° C and 100 ml of ether is added. The mixture is poured onto ice and 100 ml of ether is added. The layers are separated and the aqueous layer is back extracted with ether and the ether extracts are combined. The combined ether extracts are washed with water, saturated sodium bicarbonate (twice), water, dried and concentrated to give the crude product (III).

Provenance & Evidence