反应详情

A mixture of 63 g (0.25 mol) 2,5-dichlorothien-3-yl-sulfonyl chloride, 0.5 g sulfur monochloride and 25 g sulfuryl chloride was heated under reflux. To the refluxing reaction was then added dropwise 0.5 g aluminum trichloride in 25 g sulfuryl chloride. The reaction mixture was then heated under reflux for 3 hours, cooled diluted with 400 ml cold water and cooled, with methylene chloride. The methylene chloride extracts were washed with water, saturated aqueous sodium bicarbonate, dried over magnesium sulfate and stripped to give 62 g of 2,4,5-trichlorothien-3-ylsulfonyl chloride, which crystallized from hexane as a solid, m.p. 55° C.

1. temperaturewas heated
2. temperatureunder reflux
3. customTo the refluxing reaction
4. temperatureThe reaction mixture was then heated
5. temperatureunder reflux for 3 hours
6. temperaturecooled
7. washThe methylene chloride extracts were washed with water, saturated aqueous sodium bicarbonate
8. dry with materialdried over magnesium sulfate