Dimethylformamide dimethyl acetal → Thiourea, [(dimethylamino)methylene]phenyl-

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6.1 g. phenylthiourea and 4.3 g. dimethyl formamide dimethylacetal were suspended in 100 ml. of benzene with ~ 100 mg of p-toluene sulfuric acid and the mixture distilled through a 6 plate distilling column. The methanol-benzene azeotrope, bp 57° C, came off rapidly. After the bp rose to 80° C, the mixture was cooled and the product crystallized from the benzene. The yield was 6.3 g of solid m.p. 131°-138° C which was triturated with ether to give 6 g m.p. 139°-143° C.

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