4-Chlorophenyl Isocyanate → HCID 54055573, compound

Participants

Reaction Steps

After dissolving 14.2 g. (0.1445 mole) of 2 -imino-1 -methylpyrrolidine in anhydrous benezene, 22.2 g. (0.1445 mole) of p- chlorophenylisocyanate dissolved in anhydrous benzene is added slowly with stirring and ice-bath cooling to the above solution. Solid material forms after 10 to 15 mins. The reaction mixture is stirred at room temperature overnight. The solid is collected (m.p. = 138-141° C.) and titurated with hot CH2Cl2. The material which does not dissolve is filtered off. Removal of the methylene chloride and recrystallizations from methanol of the subsequent solid product, 1 -(1 -methyl-2 -pyrrolidylidene)-3 -p-chlorophenylurea, yields the pure material, m.p. = 142-144° C.

Provenance & Evidence