反应详情

A 6.73 g. (0.05 mole) sample of 2-imino-1-methylpyrrolidine HCl is converted to free base in the usual way. To the K 2 CO 3 -dried, benzene extracts are added a pre-filtered solution of 3,4 -dichlorophenylisocyanate (9.4 g.; 0.05 mole). Almost immediately there is a separation of product. After stirring for a short time, the product is collected and recrystallized from acetone-methanol-water and finally from acetone-water to give the pure product, 1(3,4-dichlorophenyl)-3-(1-methyl-2-pyrrolidylidene)urea. m.p. = 160°-⪆°C.

1. dry with materialTo the K 2 CO 3 -dried
2. customa separation of product
3. customthe product is collected
4. customrecrystallized from acetone-methanol-water and finally from acetone-water