HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Hexadiyne → Nona-2,4,8-triyn-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Hexadiyne | HCID 69402 | — |
| Reactant | 1-Propyn-1-ol, 3-bromo- | HCID 12180848 | — |
| Product | Nona-2,4,8-triyn-1-ol | HCID 21488150 | — |
| Product | Dodeca-2,4,8,10-tetrayne-1,12-diol | HCID 54150199 | — |
Reaction Steps
Employing a Cadiot-Chodkiewicz-type reaction, 3-bromopropyne-1-ol was reacted with 1,5-hexadiyne to give two products, 2,4,8-nonatriyne-1-ol (I) and 2,4,8,10-dodecatetrayne-1,12-diol (II), which were separated by use of appropriate solvents. Oxidative coupling of (I) gave 2,4,8,10,14,16-octadecahexayne-1,18-diol (III).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03999946 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-68ab5d91dfe149759697a89770a38e2d |
| Source note | uspto-grants-1976_12 |