HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → HCID 21488693, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | HCID 21488692 | HCID 21488692 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 21488693 | HCID 21488693 | — |
Reaction Steps
112.6 g (0.4 mole) of 1-m-chlorophenyl-3-carbethoxyamino-2-pyrazolin-5-one were methylated under hydrogen atmosphere by using 20 g of Raney nickel, 46.2 g (0.6 mole) of ammonium acetate, 27 g (0.9 mole) of paraformaldehyde, and 0.9 mole of hydrogen in a total volume of 600 ml of methanol. Hydrogenation occurred at a pressure interval of 700 to 300 psi at a temperature of 80°-100° C. Yield: 74 g (62%). Melting point: 162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000156 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-28de5950b9b1468cb739e83e9cbe95c7 |
| Source note | uspto-grants-1976_12 |