Acetic Acid → HCID 21488695, compound

HRID 1974049Notes

Reaction equation

HRID 1974049 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12](=[O:13])[CH:11]([CH3:14])[C:10]([NH:15]C(OCC)=O)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.C(O)(=O)C>[OH-].[Na+]>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12](=[O:13])[CH:11]([CH3:14])[C:10]([NH2:15])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 21488693HCID 21488693, compound

Product 1

HCID 21488695HCID 21488695, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A solution of 69 g (0.2 mole) of 1-m-chlorophenyl-3-carbethoxyamino-4-methyl-2-pyrazolin-5-one in 320 ml of 2.5 N sodium hydroxide was refluxed for 30 min. The solution was cooled and neutralized by addition of glacial acetic acid. The precipitate was dried under reduced pressure. Yield: 39 g (87%). Melting point: 138° C.

Workup

  1. temperatureThe solution was cooled
  2. customThe precipitate was dried under reduced pressure

Sources & evidence

ORD record
ord-1288939f327e45b99b8da9128f98152e
Source dataset
uspto-grants-1976_12
Patent number
US04000156

Reaction notes

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