HCID 21488580, compound → HCID 21488590, compound

HRID 1974071Notes

Reaction equation

HRID 1974071 reaction equation
[F:1][C:2]([F:24])([F:23])[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]1[CH:13]=[N:14][N:15]=[C:8]1[CH:7]=[C:6]2[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[Cl:22].I([O-])(=O)(=O)=[O:26].[Na+]>[Ru](=O)=O>[F:1][C:2]([F:24])([F:23])[C:3]1[CH:12]=[CH:11][C:10]([N:9]2[CH:13]=[N:14][N:15]=[C:8]2[CH3:7])=[C:5]([CH:4]=1)[C:6]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[Cl:22])=[O:26]

Participants

4

Reactant 2

HCID 21488580HCID 21488580, compoundHCID 23667635Sodium periodate

Product 1

HCID 21488590HCID 21488590, compound

Reagents, catalysts & solvents 1

HCID 82848Ruthenium dioxideCatalyst

Procedure

In the manner given in Example 3, 7-(trifluoromethyl)-5-(o-chlorophenyl)-s-triazolo[4,3-a]quinoline is oxidized at low temperature with sodium periodate and ruthenium dioxide to give 5-(trifluoromethyl)-2'-chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone.

Sources & evidence

ORD record
ord-4d96f2715c6c44c884c22d7ffb0b1cdc
Source dataset
uspto-grants-1976_12
Patent number
US04000151

Reaction notes

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