HCID 21488614, compound → HCID 21488589, compound

HRID 1974077Notes

Reaction equation

HRID 1974077 reaction equation
[CH3:1][C:2]1[N:6]2[C:7]3[C:12]([C:13]([C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[Cl:21])=C[C:5]2=[N:4][N:3]=1)=[CH:11][CH:10]=[CH:9][CH:8]=3.I([O-])(=O)(=O)=[O:23].[Na+]>[Ru](=O)=O>[Cl:21][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=1[C:13](=[O:23])[C:12]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N:6]1[CH:5]=[N:4][N:3]=[C:2]1[CH3:1]

Participants

4

Reactant 2

HCID 21488614HCID 21488614, compoundHCID 23667635Sodium periodate

Product 1

HCID 21488589HCID 21488589, compound

Reagents, catalysts & solvents 1

HCID 82848Ruthenium dioxideCatalyst

Procedure

In the manner given in Example 3, 1-methyl-5-(o-chlorophenyl)-s-triazolo[4,3-a]quinoline is oxidized at low temperature with sodium periodate and ruthenium dioxide to give 2'-chloro-2-(3-methyl-4H-1,2,4-triazol-4-yl)benzophenone.

Sources & evidence

ORD record
ord-f668bc32c069402ea58da43ca5063dcb
Source dataset
uspto-grants-1976_12
Patent number
US04000151

Reaction notes

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