Methyl iodide → HCID 20560022, compound

HRID 1974088Notes

Reaction equation

HRID 1974088 reaction equation
[I-:1].[NH+]1C=CC=C[CH:3]=1.[CH:8]([NH:10][C:11]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][C:12]=1[CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1)=[O:9].CI.C(NC1C=CC=CC=1CCC1C=CC=CN=1)=O>>[I-:1].[CH:8]([NH:10][C:11]1[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][C:12]=1[CH2:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N+:16]=1[CH3:3])=[O:9]

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 20559958HCID 20559958, compoundHCID 20559985HCID 20559985, compoundHCID 2186351518820-83-2

Product 1

HCID 20560022HCID 20560022, compoundYield 95%

Procedure

The pyridinium iodide is obtained by treating 2-(2-formamido-5-methoxyphenethyl)pyridine with methyl iodide according to the procedure described in Example 2 (c) for 2-(o-formamidophenethyl)pyridine. Analytically pure 2-(2-formamido-5-methoxyphenethyl)-1-methylpyridinium iodide is obtained in a yield of 95% and has a melting point of 184°-186.5° C. (corr.).

Sources & evidence

ORD record
ord-ae063f6fed5e44baaa7681b8fe4a7668
Source dataset
uspto-grants-1976_12
Patent number
US04000143

Reaction notes

Loading…