HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20559954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 6-[2-(2-Aminophenyl)ethyl]-N,N-diethylpyridine-3-carboxamide | HCID 20559955 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20559954 | HCID 20559954 | — |
Reaction Steps
6-(o-Aminophenethyl)-N,N-diethylnicotinamide N,N-diethyl-6-(o-nitrostyryl)nicotinamide (16.3 g., 0.05 mole) reduced in 150 ml. of ethanol employing 0.1 g. of 10% palladium on carbon catalyst according to the procedure described in Example 2 (a) for 2-(o-aminophenethyl)pyridine provides 6-(o-aminophenethyl)-N,N-diethylnicotinamide base. Addition of ethanolic hydrogen chloride to the nicotinamide base in ethanol provides 6-(o-aminophenethyl)-N,N-diethylnicotinamide dihydrochloride, m.p. 224°-226° C. (corr.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000143 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-497ec71c261149c09a811d18a7f88b65 |
| Source note | uspto-grants-1976_12 |