Phosphorus tribromide → Benzophenone

HRID 1974130Notes

Reaction equation

HRID 1974130 reaction equation
Cl[C:2]1[CH:3]=[CH:4][C:5](N2C(C)=NN=C2CO)=[C:6]([CH:17]=1)[C:7]([C:9]1[C:14](F)=[CH:13][CH:12]=[CH:11][C:10]=1F)=[O:8].P(Br)(Br)Br>>[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:8])[C:6]1[CH:17]=[CH:2][CH:3]=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 24614Phosphorus tribromideHCID 21488609HCID 21488609, compound

Product 1

HCID 3102Benzophenone

Procedure

In the manner given in Example 5, 5-chloro-2',6'-difluoro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone is treated with phosphorus tribromide to give 5-chloro-2',6'-difluoro-2-]3-(bromomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone.

Sources & evidence

ORD record
ord-0e66c0c9feb74ca991cc27432d795493
Source dataset
uspto-grants-1976_12
Patent number
US04000153

Reaction notes

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