Phosphorus tribromide → HCID 21488661, compound

HRID 1974152Notes

Reaction equation

HRID 1974152 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:27])[C:9]1[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:11][C:10]=1[N:19]1[C:23]([CH3:24])=[N:22][N:21]=[C:20]1[CH2:25]O.P(Br)(Br)[Br:29]>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:27])[C:9]1[CH:14]=[C:13]([C:15]([F:18])([F:17])[F:16])[CH:12]=[CH:11][C:10]=1[N:19]1[C:23]([CH3:24])=[N:22][N:21]=[C:20]1[CH2:25][Br:29]

Participants

4

Reactant 2

HCID 24614Phosphorus tribromideHCID 21488682HCID 21488682, compound

Product 1

HCID 21488661HCID 21488661, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In the manner given in Example 5, 2'-chloro-5-(trifluoromethyl)-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone is treated with phosphorus tribromide in chloroform to give 2'-chloro-5-(trifluoromethyl)-2-[3-(bromomethyl)-5-methyl-4H-1,2,4-triazol-4-yl] -benzophenone.

Sources & evidence

ORD record
ord-93d79d2cb94744e68d65f881ea8d3a5b
Source dataset
uspto-grants-1976_12
Patent number
US04000153

Reaction notes

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