Phosphorus tribromide → HCID 21488663, compound

HRID 1974157Notes

Reaction equation

HRID 1974157 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:23])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]1[C:19]([CH3:20])=[N:18][N:17]=[C:16]1[CH2:21]O.P(Br)(Br)[Br:25]>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:23])[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[N:15]1[C:19]([CH3:20])=[N:18][N:17]=[C:16]1[CH2:21][Br:25]

Participants

4

Reactant 2

HCID 24614Phosphorus tribromideHCID 21488670HCID 21488670, compound

Product 1

HCID 21488663HCID 21488663, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In the manner given in Example 5, 2'-chloro-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone is treated with phosphorus tribromide in chloroform to give 2'-chloro-2-[3-(bromomethyl)-5-methyl-4H-1,2,4-triazol-4yl]benzophenone.

Sources & evidence

ORD record
ord-8b520a7cde554e09911123fcb699910c
Source dataset
uspto-grants-1976_12
Patent number
US04000153

Reaction notes

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