Phosphorus tribromide → HCID 21488655, compound

HRID 1974166Notes

Reaction equation

HRID 1974166 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH3:21])=[N:19][N:18]=[C:17]2[CH2:22]O)=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8].P(Br)(Br)[Br:25]>C(Cl)(Cl)Cl>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH3:21])=[N:19][N:18]=[C:17]2[CH2:22][Br:25])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8]

Participants

4

Reactant 2

HCID 24614Phosphorus tribromideHCID 21488666HCID 21488666, compound

Product 1

HCID 21488655HCID 21488655, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

In the manner given in Example 5, 5-bromo-2-[3-(hydroxymethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone is treated with phosphorus tribromide in chloroform to give 5-bromo-2-[3-(bromomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]benzophenone.

Sources & evidence

ORD record
ord-0c7cabbed1fb4d6987068f787d65b7a9
Source dataset
uspto-grants-1976_12
Patent number
US04000153

Reaction notes

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