HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Phosphate, Dibasic → Methyl (2R,3R)-3-azido-4-oxoazetidine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Phosphate, Dibasic | HCID 24203 | — |
| Reactant | Potassium Persulfate | HCID 24412 | — |
| Reactant | Methyl cis-1-(2,4-dimethoxybenzyl)-3-azido-4-oxoazetidine-2-carboxylate | HCID 86734328 | — |
| Product | Methyl (2R,3R)-3-azido-4-oxoazetidine-2-carboxylate | HCID 13566680 | — |
Reaction Steps
A degassed solution of 3.8 g (0.012 mole) of methyl cis-3-azido-1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylate was treated with potassium persulfate and sodium monohydrogen phosphate as described in Preparation 2 to give methyl cis-3-azido-4-oxoazetidine-2-carboxylate which was purified by chromatography on silica gel with benzene-ethyl acetate as eluant.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000154 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-28d3675aa8e541d893d90e9ddebc09cd |
| Source note | uspto-grants-1976_12 |