2-(Bromomethyl)-3-methyloxirane → 3-Methyl-6-(2,3-epoxybutyl)benzimidazo[2,1-b]quinazolin-12(6H)one

HRID 1974284Notes

Reaction equation

HRID 1974284 reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:19])[N:7]3[C:14]4[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=4[NH:12][C:8]3=[N:9]2)=[CH:4][CH:3]=1.Br[CH2:21][CH:22]1[O:25][CH:23]1[CH3:24]>>[CH3:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:19])[N:7]3[C:14]4[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=4[N:12]([CH2:24][CH:23]4[O:25][CH:22]4[CH3:21])[C:8]3=[N:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 127416282-(Bromomethyl)-3-methyloxiraneHCID 178422974HCID 178422974, compound

Product 1

HCID 214891983-Methyl-6-(2,3-epoxybutyl)benzimidazo[2,1-b]quinazolin-12(6H)one

Procedure

3-Methyl-6-(2,3-epoxybutyl)benzimidazo[2,1-b]quinazolin-12(6H)one is prepared with 3-methylbenzimidazo[2,1-b]quinazolin-12(6H)one and 1-bromo-2,3-epoxybutane.

Sources & evidence

ORD record
ord-ab67ef00159740ca8205495031becfc5
Source dataset
uspto-grants-1976_12
Patent number
US04000275

Reaction notes

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