Ethyl bromoacetate → 6-(Carboethoxymethyl)-3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one

HRID 1974286Notes

Reaction equation

[CH3:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:19])[N:7]3[C:14]4[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=4[NH:12][C:8]3=[N:9]2)=[CH:4][CH:3]=1.Br[CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23]>>[C:22]([CH2:21][N:12]1[C:8]2=[N:9][C:10]3[C:5]([C:6](=[O:19])[N:7]2[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]1=2)=[CH:4][CH:3]=[C:2]([CH3:1])[CH:11]=3)([O:24][CH2:25][CH3:26])=[O:23]

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 178422974HCID 178422974, compound

Product 1

HCID 214892026-(Carboethoxymethyl)-3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one

Procedure

6-(Carboethoxymethyl)-3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one is prepared with 3-methylbenzimidazo[2,1-b]quinazoline-12(6H)one and ethyl bromoacetate.

Sources & evidence

ORD record: ord-1b84ebcc473b4dd182fd690754d7e9ff
Source dataset: uspto-grants-1976_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04000275

Reaction notes

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