Methyl 6-chloro-6-oxohexanoate → 6-(5-Carbomethoxypentanoyl)-3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one

HRID 1974308Notes

Reaction equation

HRID 1974308 reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=[O:19])[N:7]3[C:14]4[CH:15]=[CH:16][CH:17]=[CH:18][C:13]=4[NH:12][C:8]3=[N:9]2)=[CH:4][CH:3]=1.Cl[C:21]([CH2:23][CH2:24][CH2:25][CH2:26][C:27]([O:29][CH3:30])=[O:28])=[O:22]>>[C:27]([CH2:26][CH2:25][CH2:24][CH2:23][C:21]([N:12]1[C:8]2=[N:9][C:10]3[C:5]([C:6](=[O:19])[N:7]2[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][C:13]1=2)=[CH:4][CH:3]=[C:2]([CH3:1])[CH:11]=3)=[O:22])([O:29][CH3:30])=[O:28]

Participants

3

Reactant 2

HCID 520737Methyl 6-chloro-6-oxohexanoateHCID 178422974HCID 178422974, compound

Product 1

HCID 214891876-(5-Carbomethoxypentanoyl)-3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one

Procedure

6-(5-Carbomethoxypentanoyl)-3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one is prepared with 3-methylbenzimidazo[2,1-b]-quinazolin-12(6H)one and methyl 5-(chloroformyl)pentanoate.

Sources & evidence

ORD record
ord-f7d4c5385ef14c8da91ff6dd7b44271d
Source dataset
uspto-grants-1976_12
Patent number
US04000275

Reaction notes

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