Potassium Carbonate → HCID 21489448, compound

Participants

Reaction Steps

280 g (2 mols) of powdered potassium carbonate were suspended in 2 l of methyl ethyl ketone. 409 g (2 mols) of 4' -chlorohydroxybiphenyl were added and the mixture was heated to the boil. Thereafter 269 g (2 mols) of α-chloropinacolone were added dropwise over the course of 1 hour and the mixture was heated for 15 hours under reflux. After cooling, the solid residue was filtered off, washed and recrystallized from ligroin. 513 g (79% of theory) of 1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one of melting point 90° C were obtained.

Provenance & Evidence