HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → HCID 178484983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 1-Cyano-2,3-dimethylisothiourea | HCID 111103 | — |
| Reactant | HCID 178433288 | HCID 178433288 | — |
| Product | HCID 178484983 | HCID 178484983 | — |
Reaction Steps
A solution of 4-methyl-5-[(2-aminoethyl)thiomethyl]-imidazole (17.0 g.) and N-cyano-N',S-dimethylisothiourea (11.2 g.) in acetonitrile (500 ml) was heated under reflux for 24 hours. Following concentration, the residue was chromatographed on a column of silica gel with acetonitrile as eluant and the product obtained was finally recrystallised from acetonitrile-ether to yield N-cyano-N'-methyl-N"-[2-((methyl-5-imidazolyl)methylthio)ethyl]guanidine m.p. 141°-2°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04000302 |
| Source dataset | uspto-grants-1976_12 |
| ORD ID | ord-4c35cc35085c4abea79f135f857a6498 |
| Source note | uspto-grants-1976_12 |